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Exit Project

What is more interesting than the human condition? And how about looking at some genetics along with the human condition?

Your exit project is to design and produce an informational genetic disease/disorder brochure to educate and enlighten your fellow classmates on one of the myriad of genetic diseases that are currently being researched.

You can gather your information from textbooks, newspapers, magazines, medical journals, organizations, on-line resources and interviews; or other resources that you can find. You will also need art supplies....many of which I can supply for you. You have three weeks to finish and present your brochure to the class. All the work can be done in class, so get started!! Here is what you need to do:

procedure:
1.	Choose your disease.
2.	Research the disease.
3.	Make an outline of the information found
4.	Arrange your information in the correct format.
5.	Develop your brochure/pamphlet.

observations:	Finished brochure/pamphlet
1.	be easy to read
2.	be scientifically accurate
3.	be comprehensive (contain all required information)
4.	grammatically correct and contain no spelling errors
5.	be attractive to the eye, colorful
6.	have all scientific terms explained or defined

Required Information
cover:	Name of your disorder
1.	large and colorful!!

front fold:
1.	cause
a.	Is this caused by one gene or a combination of genes?
b.	What gene/s is/are affected?
c.	Identify the protein that is not adequately being produced by the faulty gene
d.	Describe the normal function of this protein
e.	Is this an autosomal or sex-linked trait
f.	What type of gene inheritance is demonstrated
	1) dominant or recessive
	2) codominant
	3) multiple alleles
	4) gene amplification
g.	Explain the type of gene mutation noted above
2.	Gene Loci
a.	On which numbered chromosome(s) is the gene or genes located
b.	State the specific loci of the gene (such as P or Q arm ex. P22.364)
c.	Try to include a photo of the chromosome map indicating the specific gene loci

inside middle:
1.	Statistics
a.	Are more males or females affected?
b.	Are there any religious groups that have a higher incidence of this disorder?
c.	Are there any ethnic groups that seem to have a higher incidence of this disorder?
d.	What is the life expectancy of someone with this disorder?
e.	At what age does one start to exhibit symptoms?
f.	What is the incidence of this genetic disorder? (How common is this disorder?)
2.	Symptoms (characteristics of this disorder)
a.	Patient's symptoms
	1) Physical
	2) Mental (describe their ability to think and to learn, mental age or IQ)
	3) Emotional
b.	Family's symptoms
	1) Describe the impact on the rest of the family. How does having a child with this disorder impact upon the rest of the family?
	*does this child require additional care and attention compared to the rest of the family?
	*will having a child with this disorder impact financially on the family?
3.	diagnostic testing
a.	Are there any prenatal tests to diagnose this condition prior to birth? If so:
	1) What is the test?
	2) Describe how the tests are performed.
	3) At what time during the pregnancy should the testing be performed?
	4) Does the test pose any risk to the unborn child? If so, what?
b.	Are there any screening tests that can be performed on the parents prior to the pregnancy to determine if they are carriers? If so:
	1) What are the tests?
	2) How are they performed?

back fold:
1.	Current treatment
a.	Are there any medications that can be given? If so:
	1) What is the medicine? (be specific)
	2) What is the purpose of the medicine?
	3) When and how is it taken?
b.	Does the person's diet need to be adjusted? If so, how? What foods need to be included/omitted? Why?
c.	Is physical therapy suggested? If so, describe the type of therapy to be administered.
d.	Is gene therapy possible? If so, how is the gene administered?
e.	Is surgery necessary? If so:
f.	Other
2.	Pedigree
a.	Try to include a standard circle/square standard pedigree which demonstrates the pattern of inheritance (You may download this from the computer, or photocopy one from a text)
b.	You may also construct a fictitious pedigree that correctly demonstrates the pattern of inheritance.
	1) Include a key
	2) Include a brief explanation of the pedigree
	3) Include at least three generations of a family

back middle:
	Your name
	Genetics Unit
	Mariemont High School AP Exit Project

and don't forget......
	****PICTURES ARE GREAT....
	****BIBLIOGRAPHY....where did you get your info? MLA, please.